Vitamin D should be used with cautions in infants, who may have increased sensitivity to its effects, and in patient with renal impairment or calculi, or heart disease, who might be at increased risk of organ damage if hypercalcemia occurred.
Plasma phosphate concentration should be controlled during vitamin D therapy due to the risk of ectopic calcification.
It is advised that patients receiving pharmacological doses of vitamin D should have their plasma calcium concentration monitored at regular intervals, especially initially or if symptoms suggests toxicity, and in infants if they are breast-fed by mothers receiving pharmacological doses of vitamin D.
Dose should be monitored by testing for serum vitamin D level.
Effects on the Ability To Drive and Operate Machine: Pacific Nature's Vitamin D3 5000 IU has no influence on the ability to drive or use machine.